Publications
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- MD Diaz*, RM Kandell*, JR Wu, A Chen, KL Christman†, EJ Kwon†. Infusible Extracellular Matrix Biomaterial Promotes Vascular Integrity and Modulates the Inflammatory Response in Acute Traumatic Brain Injury. Advanced Healthcare Materials, 2023. [ Open Access ]
- JA Kudryashev, MI Madias, RM Kandell; QX Lin, EJ Kwon†. An Activity-Based Nanosensor for Minimally-Invasive Measurement of Protease Activity in Traumatic Brain Injury. Advanced Functional Materials, 2023. [ Open Access ]
- JR Wu, Y Hernandez, KF Miyasaki, EJ Kwon†. Engineered nanomaterials that exploit blood-brain barrier dysfunction for delivery to the brain. Advanced Drug Delivery Reviews, 114820. [ Open Access ]
- MT Spang, R Middleton, M Diaz, J Hunter, J Mesfin, A Banka, H Sullivan, Wang R, TS Lazersn, S Bhatia, J Corbitt, G D’Elia, G Sandoval-Gomez, R Kandell, MA Vratsanos, K Gnanasekaran, T Kato, S Igata, C Luo, KG Osborn, N Gianneschi, O Eniola-Adefeso, P Cabrales, E Kwon, F Contijoch, RR Reeves, AN Demaria, KL Christman. Healing Tissues From the Inside Out: Infusible Extracellular Matrix Biomaterial for Targeting and Treating Inflammatory Tissues via Intravascular Administration. Nature Biomedical Engineering, 2023, 7 (2), 94-109.
- LE Waggoner, KF Miyasaki, EJ Kwon†. Analysis of PEG-lipid Anchor Length on Lipid Nanoparticle Pharmacokinetics and Activity in a Mouse Model of Traumatic Brain Injury. Biomaterials Science, 2023, 11, 4238 - 4253. [ Open Access ]
- A Almenar-Queralt; RS Chaves; EJ Kwon; SB Shah. Heads Up! Interlinked Amyloidogenic and Axonal Transport Pathways in Concussion-induced Neurodegeneration. Neuroscience Insights, 2022.
- Waggoner, LE; Kang, JY; Zuidema, J; Hurtado, AA; Vijaykumar, S; Sailor, MJ; Kwon, EJ†. Porous Silicon Nanoparticles Targeted to the Extracellular Matrix for Therapeutic Protein Delivery in Traumatic Brain Injury. Bioconjugate Chemistry, 2022. ACS Editors' Choice Article.
- Kandell RM*, Kudryashev JA*, Kwon EJ. Targeting the Extracellular Matrix in Traumatic Brain Injury Increases Signal Generation from an Activity-Based Nanosensor. ACS Nano, 2021, 15(12): 20504-20516.
- Waggoner LE, Madias MI, Hurtado AA, Kwon EJ. Pharmacokinetic analysis of peptide-modified nanoparticles with engineered physicochemical properties in a mouse model of traumatic brain injury. AAPS Journal, 2021, 23(5), 1-12.
- Chan LW, Hern KE, Ngambenjawong C, Lee K, Kwon EJ, Hung DT, Bhatia SN. Selective Permeabilization of Gram-Negative Bacterial Membranes Using Multivalent Peptide Constructs for Antibiotic Sensitization. ACS Infectious Diseases, 2021, 7(4), 721-732.
- Kwon EJ*†, Ko H*, Bhatia SN. Peptide Spiders: Peptide-Polymer Conjugates to Traffic Nucleic Acids. Mol Pharm., 2020, 17 (9), 3633-3642.
- Kandell RA*, Waggoner LE*, Kwon EJ. Nanomedicine for Acute Brain Injuries: Insight from Decades of Cancer Nanomedicine. Mol Pharm., 2020. 10.1021/acs.molpharmaceut.0c00287
- Kudryashev JA, Waggoner LE, Leng HT, Mininni NH, Kwon EJ. An Activity-Based Nanosensor for Traumatic Brain Injury. ACS Sensors, 2020, 5 (3), 686-692. Rising Stars in Sensing.
- Bertucci A, Kim KH, Kang J, Zuidema JM, Lee S, Kwon E, Kim D, Howell SB, Ricci F, Ruoslahti E, Jang HJ, Sailor MJ. Tumor-targeting, microRNA-silencing Porous Silicon Nanoparticles for Ovarian Cancer Therapy. ACS Applied Materials & Interfaces, 2011(27), 23926-23937.
- Lo JH, Hao L, Muzumdar MD, Raghavan S, Kwon EJ, Pulver EM, Hsu F, Aguirre AJ, Wolpin BM, Fuchs CS, Hahn WC, Jacks T, Bhatia SN. iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer. Molecular Cancer Therapeutics, 17(11): 2377-2388.
- Kwon EJ, Skalak M, Bertucci A, Braun G, Ruoslahti E, Sailor MJ, Bhatia SN. Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-infectives for the Treatment of P. aeruginosa Lung Infections. Advanced Materials, 2017, 29(35).
- Kwon EJ*, Dudani JS*, Bhatia SN. Ultrasensitive tumour-penetrating nanosensors of protease activity. Nature Biomedical Engineering, 2017, 1: 0054.
- Lo JH*, Kwon EJ*, Zhang AQ, Singhal PS, Bhatia SN. A comparison of modular PEG incorporation strategies for stabilization of peptide-siRNA nanocomplexes. Bioconj Chem, 2016, 27(10): 2323-2331.
- Kwon EJ, Skalak M, Lo Bu R, Bhatia SN. A Neuron-Targeted Nanoparticle for siRNA Delivery to Traumatic Brain Injuries. ACS Nano, 2016, 10 (8), 7926–7933.
- Kang J, Joo J, Kwon EJ, Skalak M, Hussain S, She Z, Ruoslahti E, Bhatia SN, Sailor MJ. Self-sealing prous silicon-calcium silicate core-shell nanoparticles for targeted siRNA delivery to the injured brain. Advanced Materials, 2016, 28(36), 7962-7969.
- Joo J, Kwon EJ, Kang J, Skalak M, Anglin EJ, Mann AP, Ruoslahti E, Bhatia SN, Sailor MJ. Porous silicon-graphene oxide targeted delivery of siRNA to the injured brain. Nanoscale Horizons. 2016,1, 407-414.
- Mann AP, Scodeller P, Hussain S, Joo JM, Kwon EJ, Braun G, Molder T, She ZG, Kotamraju V, Ranscht B, Krajewski S, Teesalu T, Bhatia SN, Sailor MJ, Ruoslahti E. A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries. Nat Commun, 2016; 7:11980.
- Kwon EJ, Lo JH, Bhatia SN. Smart Nanosystems: Bio-inspired Technologies that Interact with the Host Environment. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14460-6.
- Siegert S, Seo J, Kwon EJ, Rudenko A, Cho S, Wang W, Flood Z, Martorell AJ, Ericsson M, Mungenast AE, Tsai LH. The schizophrenia risk gene product miR-137 alters presynaptic plasticity. Nat Neurosci. 2015, 18(7):1008-16.
- Lin KY, Kwon EJ, Lo JH, Bhatia SN. Drug-induced amplification of nanoparticle targeting to tumors. Nanotoday. 2014, 9(5):550-559.
- Wang W, Kwon EJ, Tsai LH. MicroRNAs in learning, memory, and neurological diseases. Learning and Memory. 2012, 19(9):359-368.
- Kwon EJ, Wang W, Tsai LH. Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets. Mol Psychiatry. 2011, 18(1):11-2.
- Kwon EJ, Liong S, Pun SH. A truncated HGP peptide sequence that retains endosomolytic activity and improves gene delivery efficiency. Mol Pharm. 2010, 7(4):1260-5.
- Kwon EJ, Lasiene J, Jacobson BE, Park IK, Horner PJ, Pun SH. Targeted nonviral delivery vehicles to neural progenitor cells in the mouse subventricular zone. Biomaterials. 2010, 31(8):2417-24.
- Kwon EJ, Bergen JM, Park IK, Pun SH. Peptide-modified vectors for nucleic acid delivery to neurons. J Control Release. 2008, 132(3): 230-235.
- Kwon EJ, Bergen JM, Pun SH. Application of an HIV gp41-derived peptide for enhanced intracellular trafficking of synthetic gene and siRNA delivery vehicles. Bioconjug Chem. 2008, 19(4):920-7.
- Bergen JM, Kwon EJ, Shen TW, Pun SH. Application of an environmentally sensitive fluorophore for rapid analysis of the binding and internalization efficiency of gene carriers. Bioconjug Chem. 2008, 19(1):377-84.
- Cellitti J, Llinas M, Echols N, Shank EA, Gillespie B, Kwon E, Crowder SM, Dahlquist FW, Alber T, Marqusee S. Exploring subdomain cooperativity in T4 lysozyme I: structural and energetic studies of a circular permutant and protein fragment. Protein Sci. 2007 May;16(5):842-51.
